Inositol for the treatment of depression and mood swings

Issue: 22 - 30 Jun 2008
I would like to introduce you to Inositol which is a new product we have in our clinic and on our shopping carts, we are very excited about this supplement as it helps with depression, mood swings and a lot of other physiological problems that we see today. I have found that a lot of the prescribed drugs e.g. anti-depressants have nasty side effects and can be habit forming, so it is fantastic to have a natural supplement that can take the place of some of these drugs. The research that has been done on Inositol up to date looks very promising.
Below you will see there are many other areas besides psychiatry that Inositol can really make a difference to.
Inositol is needed for health at a cellular level
Inositol plays an important part in the health of cell membranes especially the specialized cells in the brain, bone marrow, eyes, and intestines. The function of the cell membranes is to regulate the contents of the cells, which makes effective functioning possible.
Inositol is a simple carbohydrate (sugar) that plays an important role in chemical reactions in the body associated with the production of glucose. Inositol facilitates communication between neurons and helps the nervous system to function.
Although Inositol is sometimes called a member of the B complex of vitamins, it is really not a vitamin. Vitamins are considered essential to the health & function of our bodies & although Inositol is valuable, it is not essential, having said that, Inositol performs some important functions in the body, working closely with the entire Vitamin B Complex as well as with Choline.
There are many areas where Inositol can play a huge part in our health & well-being:
  • Psychiatry (depression, panic attacks, & obsessive compulsive disorder)
  • Mood swings
  • Bodybuilding
  • Increased energy
  • Lower Cholesterol
  • Diabetes
  • Numbness & nerve damage due to diabetes
  • Fat Metabolism
  • Hair growth
  • Constipation (due to its stimulating effect on the muscular action of the alimentary canal)
  • Insomnia
  • Fatty Liver

Inositol and body building
Inositol is necessary for many physiological processes. It is used by the body to form cell membranes and it allows for the proper functioning of cells. As a dietary and exercise aide, Inositol assists in the transmission of nerve signals, and helps to transport lipids within the body. This will help contract your muscles more efficiently and will help you to use body fat as fuel for your workouts.
Controlled trials of Inositol in psychiatry by
Levine J
Ministry of Health Mental Health Center,
Faculty of Health Sciences,
Ben Gurion University of the Negev, Beersheva, Israel
Eur Neuropsychopharmacol, 1997 May, 7:2, 147-55
Inositol is a simple polyol precursor in a second messenger system important in the brain. Cerebrospinal fluid Inositol has been reported as decreased in depression. A double-blind controlled trial of 12 g daily of Inositol in 28 depressed patients for four weeks was performed. Significant overall benefit for Inositol compared to placebo was found at week 4 on the Hamilton Depression Scale. No changes were noted in hematology, kidney or liver function. Since many antidepressants are effective in panic disorder, twenty-one patients with panic disorder with or without agoraphobia completed a double-blind, placebo-controlled, four week, random-assignment crossover treatment trial of Inositol 12 g per day. Frequency and severity of panic attacks and severity of agoraphobia declined significantly with Inositol compared to placebo. Side-effects were minimal. Since serotonin re-uptake inhibitors benefit obsessive compulsive disorder (OCD) and Inositol is reported to reverse desensitization of serotonin receptors, thirteen patients with OCD completed a double-blind controlled crossover trial of 18 g Inositol or placebo for six weeks each. Inositol significantly reduced scores of OCD symptoms compared with placebo. A controlled double-blind crossover trial of 12 g daily of Inositol for a month in twelve anergic schizophrenic patients, did not show any beneficial effects. A double-blind controlled crossover trial of 6 g of Inositol daily vs. glucose for one month each was carried out in eleven Alzheimer patients, with on clearly significant therapeutic effects. Antidepressant drugs have been reported to improve attention deficit disorder (ADDH) with hyperactivity symptomatology. We studied oral Inositol in children with ADDH in a double-blind, crossover, and placebo-controlled manner. Eleven children, mean age 8.9 +/- 3.6 years were enrolled in an eight week trial of Inositol or placebo at a dose of 200 mg/kg body weight. Results show a trend for aggravation of the syndrome with Myo-Inositol as compared to placebo. Recent studies suggest that serotonin re-uptake inhibitors are helpful in at least some symptoms of autism. However a controlled double-blind crossover trial of Inositol 200 mg/kg per day showed no benefit in nine children with autism. Cholinergic agonists have been reported to ameliorate electroconvulsive therapy (ECT)-induced memory impairment. Inositol metabolism is involved in the second messenger system for several muscarinic cholinergic receptors. Inositol 6 g daily was given in a crossover-double-blind manner for five days before the fifth or sixth ECT to a series of twelve patients, without effect. These results suggest that Inositol has therapeutic effects in the spectrum of illness responsive to serotonin selective re-uptake inhibitors, including depression, panic and OCD, and is not beneficial in schizophrenia, Alzheimer's ADDH, autism or ECT-induced cognitive impairment.
Foods high in inositol
  • Nuts
  • Beans
  • Whole Grains especially wheat and wheat bran
  • Fruit especially Cantaloupe and Oranges
  • Vegetables
  • Legumes
  • Molasses (blackstrap)
1 to 2 teaspoons daily on an empty stomach.
Mix with water or juice.
Available in 100gm oral powder
100% pure free form Inositol
Myorthotics & Naturopathic Consultations
As of the 30th July there will be a price rise for consultations.
Due to rising costs our fees have increased to the prices below
Myorthotics Consultation... $75
Naturopathic Consultation 1st... $115
Naturopathic follow-up... $75
We have managed to keep our fees the same for the last 3 years but unfortunately we have to increase them slightly.
"I have a constant feeling of well being. I find that when I started taking the Natural HGH my sleeping really improved and I was waking up in the morning refreshed and full of energy. I now find that my energy is not only excellent but I maintain it throughout the day, not needing those afternoon naps anymore."
Joan, Retired Nurse, QLD

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